ALTHOUGH radioactive isotope photoscanning of the liver has been performed for over ten years, there are few critical appraisals of its value to the surgeon. This laboratory test has been reported to yield correctly interpreted results in 73% to 93% of cases evaluated and to be more reliable than other nonoperative methods for detecting metastatic liver disease. Little differentiation between medical and surgical lesions has been made in these reports.1-4 In order to determine the relative value of this test to the surgeon, the records of patients having a liver scan between April 1, 1963, and April 1, 1967, were reviewed and the accuracy of liver scan compared with the laparotomy and biopsy findings and the serum alkaline phosphatase and sulfobromophthalein (Bromsulphalein) (BSP) tests.
Radioactive isotope liver scans were performed in 642 patients; however, only 304 had confirmation of the diagnosis by biopsy of the liver, laparotomy, or
Smith LB, Williams RD. The Relative Diagnostic Accuracy of Liver Radioactive Isotope Photoscanning. Arch Surg. 1968;96(5):693-697. doi:10.1001/archsurg.1968.01330230001001