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Article
January 1969

Peutz-Jeghers Syndrome With Metastases to an Abdominal Incision

Author Affiliations

Madison, Wis
From the Division of Clinical Oncology and the Department of Surgery (Dr. Mackman), the Health Service and the Department of Medicine (Dr. Perna), and the Department of Pathology (Dr. Gossett), University of Wisconsin Medical Center, Madison.

Arch Surg. 1969;98(1):99-102. doi:10.1001/archsurg.1969.01340070117026
Abstract

Peutz-Jeghers syndrome consisting of the triad-gastrointestinal-polyps, mucocutaneous pigmentation, and familial history is a well recognized clinical entity.1,2 The polyps which are generally in the small intestine but which may be found throughout the gastrointestinal tract, are peculiar in that they contain all types of epithelial cells found in the gut arranged in the usual manner on a branching muscular stroma, and are thus felt to represent hamartomatas.3,4 Because of this unusual histological appearance, they have often been misinterpreted as invading muscularis and are thus considered by some as being malignant in 15% to 20% of cases.1 In reality, only six of the more than 300 cases reported have the polyps shown definite malignancy with metastases.5 The following case records the unusual occurrence of a metastases to the abdominal wall in a patient with Peutz-Jeghers syndrome.

Report of a Case  This 22-year-old white man was first seen

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