July 1969

Arteriovenous Perfusion With the Disc OxygenatorTreatment of Acute Respiratory Failure

Author Affiliations

From the departments of surgery and biochemistry and the Medical Research Council of Canada, Laval University (Drs. Awad, Brassard, and Caron and Mr. Nadeau); and the Department of Cardiopulmonary Physiology, Laval Hospital (Dr. Roy); Quebec.

Arch Surg. 1969;99(1):69-74. doi:10.1001/archsurg.1969.01340130071013

ALTHOUGH commonly used in cardiac surgery, the artificial oxygenator has only rarely been employed in the support of the failing respiratory system. Furthermore the majority of these attempts were performed by means of a partial venoarterial1 or venovenous bypass2,3 which consequently necessitates the use of one or more pumps and thus complicates the technique and increases the trauma to the blood. Recently Rashkind et al4 evaluated a small bubble oxygenator of their construction and used an arteriovenous type of bypass. They postulated this method for the treatment of infants and newborns suffering from the respiratory distress syndrome. From these experiments, they concluded that the cardiac output and cardiac work during these perfusions was not increased over that of hypoxic puppies.5

The purpose of the following investigation was twofold: first, to determine the capability of the disc oxygenator when used as an arteriovenous bypass in sustaining the

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