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IN the minds of the majority of physicians today, intravenous anesthesia means the ultrashort-acting barbiturates, such as thiopental sodium. Many anesthesiologists, however, do not consider these agents as truly anesthetic, since they possess no analgesic potency and act by central depression.
Other intravenous anesthetic agents which are distinctly different from the ultrashort-acting barbiturates have either been introduced, or are soon to be. They are potent drugs which, susceptible as they are to misuse due to administration, can do patients serious, even fatal, harm. This will lead to severe and unjust criticism of the drugs.
Innovar, a combination of droper-idol, a powerful long-acting tranquilizer and fentanyl citrate, a very potent short-acting narcotic, has been found acceptable by many anesthesiologists for the induction and maintenance of anesthesia combined with nitrous oxide-oxygen. This agent may also be used very satisfactorily to enable endoscopy under topical anesthesia, as basic sedation for other procedures, and
DILLON JB. Intravenous Anesthesia: A Warning. Arch Surg. 1970;101(4):541. doi:10.1001/archsurg.1970.01340280093026