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March 1971

Renal Vein Sampling in the Awake Intact Baboon

Author Affiliations

From the Department of Surgery, University of Illinois College of Medicine, and the Abraham Lincoln School of Medicine, Chicago. Dr. Reed is a Wellcome Foundation Traveling Scholar.

Arch Surg. 1971;102(3):195-196. doi:10.1001/archsurg.1971.01350030033008

To establish a technique for chronic renal vein catheterization in the primate, PE 240 catheters were introduced into the renal vein through the vena cava and led extraperitoneally to a subcutaneous pocket in the back in 17 baboons. After five to seven days, 14 were patent. Values for para-aminohippurate extraction EPAH and for oxygen tension (Po2) and pressure gradients between the renal vein and cava are presented. The mean EPAH was 81.4% ± 5.3 (95% confidence limits [CL]). The mean renocaval pressure gradient was 18.0 mm Hg ± 5.2 (95% CL). The mean renocaval Po2 gradient was 6.0 mm Hg ± 3.3 (95% CL).