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August 1971

Vagotomy Limited to the Parietal Cell MassPreliminary Patient Studies

Author Affiliations

From the Department of Surgery, University of Illinois, the Abraham Lincoln School of Medicine, and the Veterans Administration West Side Hospital, Chicago. Dr. Condon is now with the University of Iowa College of Medicine, Iowa City.

Arch Surg. 1971;103(2):153-157. doi:10.1001/archsurg.1971.01350080069010

This is a pilot study of parietal cell vagotomy with Finney pyloroplasty in the human. Twenty-five patients had preoperative and postoperative gastric secretory studies and their cases were followed from eight months to 2½ years. Results may be summarized: (1) Basal gastric acid secretion was reduced an average of 39% to 4.20 mEq/hr. (2) Maximal acid secretory capacity of the stomach was reduced by 50% to 13.36 mEq/hr. (3) Duodenal ulcer symptoms were abolished by all patients. (4) No patient developed diarrhea or any other symptoms of the postvagotomy syndrome. This study demonstrates that the procedure may be done with safety, that it is, in the short term, effective in the treatment of duodenal ulcer, and that it does produce a significant reduction in gastric acid secretion without accompanying postvagotomy symptoms.