The records of 101 consecutive patients with adenocarcinoma of the pancreas indicated that diagnostic, palliative, and potentially curative operations were all associated with a high operative mortality. Relief of symptoms was accomplished in 53% of patients surviving palliative operations, 78% surviving chemical splanchnicectomy, and 67% surviving pancreaticoduodenectomy. Palliative biliary and gastric decompression did not significantly prolong survival. "Curative" pancreaticoduodenectomy, while it failed to effect a cure, provided the best method of palliation.
Feduska NJ, Dent TL, Lindenauer SM. Results of Palliative Operations for Carcinoma of the Pancreas. Arch Surg. 1971;103(2):330-334. doi:10.1001/archsurg.1971.01350080246039