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August 1971

Effect of Cryotherapy on Tracheal Tumors in Rats

Author Affiliations

Columbus, Ohio
From the Department of Surgery, Ohio State University College of Medicine, Columbus.

Arch Surg. 1971;103(2):341-343. doi:10.1001/archsurg.1971.01350080257041

Implants of Walker 256 carcinosarcoma were placed between the thyroid isthmus and trachea of rats. After the tumor had invaded the trachea, the tumor mass and the involved area of trachea were frozen with a cryoprobe. Necropsy studies demonstrated complete erradication of tumor without permanently altering the gross architecture of the trachea. Cryotherapy may be of value in the management of selected patients with neoplasms of the trachea.