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April 1972

Bilateral Impedance Rheography in the Diagnosis of Deep Venous Thrombosis of the Legs

Author Affiliations

Irvine, Calif
From the Department of Surgery, University of California, Irvine, Calif. Sponsored by John E. Connolly, MD.

Arch Surg. 1972;104(4):515-519. doi:10.1001/archsurg.1972.04180040129022

Impedance rheography in conjunction with a respiratory maneuver has proven to be useful in the detection of deep venous thrombosis of the legs. In a study of 25 normal volunteers, there were no changes in base-line impedance of less than 0.19% following deep inspiration. Two hundred fortyfive patients were studied; 45 patients had responses at or below 0.19%, and in 40 cases, deep venous thrombosis was proven or strongly suspected. In a prospective study of 64 patients, deep venous thrombosis was diagnosed six times and confirmed by venography in each case. However, four patients exhibited a false-positive result which appears to be a significant limitation of the method. Preliminary studies have shown that variation in the respiratory maneuver may eliminate the false-positive responses.