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October 1972

Perforation of the Ileum

Author Affiliations

USAF, Baltimore
From the Department of Surgery, the Johns Hopkins University School of Medicine and the Johns Hopkins Hospital, Baltimore.

Arch Surg. 1972;105(4):550-552. doi:10.1001/archsurg.1972.04180100005003

Perforation of the terminal ileum occurred in 163 patients. Although the cause of this acute abdominal catastrophy, still common in Asia and Africa, is not clear, the typical macrophage reaction of typhoid fever was seen in five of eight carefully studied patients. In only one of the five patients, the typhoid organisms grew from a culture. Although the mortality following simple closure was 28%, it was lower than that for resectional treatment.