Metastases from clear-cell carcinoma of the kidney may occur anywhere in the body many years following removal of the primary tumor. The case of a 66-year-old patient is presented who was found to have the typical features of a periampullar carcinoma. This was treated by total pancreatectomy and found to be a metastatic nodule of a clear-cell carcinoma of the kidney, the patient having undergone right nephrectomy for this lesion 13 years earlier.
Four cases of pancreatic metastases from a renal cell carcinoma have been found in the literature, but this seems to be the first described case in which the metastases was specifically in the periampullar region.
Guttman FM, Ross M, Lachance C. Pancreatic Metastasis of Renal Cell Carcinoma Treated by Total Pancreatectomy. Arch Surg. 1972;105(5):782-784. doi:10.1001/archsurg.1972.04180110099026