A patient with Fabry's disease underwent cadaveric renal transplantation. Unusual features of this case were as follows: (1) partial correction of the enzyme deficiency typical of the disease by the renal allograft; (2) the development of rapidly progressive pulmonary vascular obstruction and eventual fatal pulmonary embolism from subclavian vein thrombosis; and (3) surgical clipping of the inferior vena cava. This was done because of failure of and complications from anticoagulant therapy and did not in any way alter allograft function.
Suros J, Woods JE, Anderson CF, Frohnert PP, Kazmier FJ, Holley KE, Riley FC, DeWeerd JH. A Kidney Transplant Patient With Fabry's DiseaseUnusual Features. Arch Surg. 1973;106(2):231-233. doi:10.1001/archsurg.1973.01350140087026