Twenty-seven cases of histologically proven carcinoma of the male breast were reviewed and compared with 2,387 cases of mammary carcinoma in women.
Men were significantly older than women at the time of diagnosis and more often reported trauma to the breast. They also had a higher incidence of local advancement which was not associated with a longer delay in seeking treatment.
No sex specific difference in survival was found when relative survival was determined for all cases from the first sign of disease, and men appeared to be no less curable than women when treated with radical mastectomy for comparable stages of the disease.
Men with advanced disease frequently benefited by hormone and endocrine manipulation and one had an unprecedented response to androgen therapy.
Donegan WL, Perez-Mesa CM. Carcinoma of the Male BreastA 30-Year Review of 28 Cases. Arch Surg. 1973;106(3):273-279. doi:10.1001/archsurg.1973.01350150013005