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April 1973

Mumps Virus and BCG Vaccine in Metastatic Melanoma

Author Affiliations

Columbus, Ohio
From the Department of Surgery, Ohio State University College of Medicine, Columbus.

Arch Surg. 1973;106(4):503-506. doi:10.1001/archsurg.1973.01350160117019

Eight patients with metastatic melanoma were treated with surgical excision of the tumor, chemotherapy, BCG vaccine, and killed mumps virus injections. Five of these eight patients had additional clinical control of their malignant melanoma when killed mumps virus was added to the immunological stimulation sequence. The dramatic clinical benefit of immunologic stimulation with killed mumps virus in melanoma patients is believed to be transient.