Three methods of donor site management were tested in 17 patients to determine if any resulted in faster wound healing. Gross inspection and biopsies revealed no differences between donor sites left uncovered or those treated with fine mesh gauze. However, porcine xenograft coverage resulted in a significant incidence (35%) of increased inflammation and delayed repair, making it an unsuitable dressing for fresh donor sites.
Salisbury RE, Wilmore DW, Silverstein P, Pruitt BA. Biological Dressings for Skin Graft Donor Sites. Arch Surg. 1973;106(5):705-706. doi:10.1001/archsurg.1973.01350170069017