Hepatic hemangiomas that become clinically apparent in newborn infants are life-threatening lesions. Death is usually caused by either congestive heart failure due to arteriovenous shunt, rupture with fatal hemorrhage, or thrombocytopenia with massive hemolysis and hemorrhage.
Two cases of giant cavernous hemangiomas of the liver in newborn infants occurred. The masses were felt shortly after birth. Successful resection of the tumors by hepatic lobectomy was carried out without morbidity, mortality, or permanent derangement of liver function.
Administration of corticosteroids offers an alternative treatment for extensive hepatic hemangioma. Hepatic lobectomy is the treatment of choice for infants with tumor localized in one lobe.
Matolo NM, Johnson DG. Surgical Treatment of Hepatic Hemangioma in the Newborn. Arch Surg. 1973;106(5):725-727. doi:10.1001/archsurg.1973.01350170085023