October 1973

Gastrin Levels Following Thermal Injury

Author Affiliations

Fort Sam Houston, Tex
From the US Army Institute of Surgical Research, Brooke Army Medical Center, Fort Sam Houston, Tex. Dr. McGuigan is now with the Division of Gastroenterology, J. Hillis-Miller Health Center, University of Florida, Gainesville.

Arch Surg. 1973;107(4):622-624. doi:10.1001/archsurg.1973.01350220098021

Serum gastrin levels have been measured in a group of patients with extensive thermal injuries. They are not altered by burn injury nor do they correlate significantly with burn size, sepsis, or occurrence of gastroduodenal ulceration.

These findings are consistent with previous acid secretory studies and suggests that Curling ulcer diathesis is determined primarily by defects in the barrier function of the gastric mucosa rather than by abnormal acid production.