Two patients developed acute appendicitis secondary to metastatic mammary carcinoma. This unusual occurrence may become more common as increased survival for patients with metastatic adenocarcinoma is achieved, and it should be emphasized that chemotherapy can remarkably alter symptoms, signs, and management of such patients. If oophorectomy is performed in such a patient, appendectomy should be done concomitantly.
Burney RE, Koss N, Goldenberg IS. Acute Appendicitis Secondary to Metastatic Carcinoma of the BreastA Report and Review of Two Cases. Arch Surg. 1974;108(6):872-875. doi:10.1001/archsurg.1974.01350300102025