September 1974

Penicillin and Épluchage Treatment of Hepatic Actinomycosis

Author Affiliations

From the Department of Surgery, Veterans Administration Hospital, Salem, Va, and the University of Virginia Medical Center, Charlottesville. Dr. Prioleau is now with the Division of Plastic Surgery, Duke University Medical Center, Durham, NC.

Arch Surg. 1974;109(3):426-429. doi:10.1001/archsurg.1974.01360030078020

Primary hepatic actinomycosis is extremely rare. The most effective treatment of actinomycosis is generally thought to be a combination of wide surgical excision and intensive, long-term penicillin therapy. In the case presented, prolonged penicillin therapy and removal of involved hepatic tissue in multiple-staged operative procedures were employed successfully. The patient died 27 months after the diagnosis of his disease, following prolonged alcoholic ingestion. He had no evidence of active actinomycosis when last examined ten weeks prior to his death.