October 1974


Author Affiliations

Albany, NY


by Edward Paloyan, Anne Lawrence, and Francis Straus, $16, Grune & Stratton Inc, 1973.

Arch Surg. 1974;109(4):591. doi:10.1001/archsurg.1974.01360040099038

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This monograph presents, in repetitious detail, the unorthodox attitudes of the authors regarding the clinical and pathologic characteristics of primary hyperparathyroidism and its surgical treatment. The scientific facts on which these attitudes are based are qualitatively accurate, but the quantitative conclusions appear to be exaggerated in many instances. As examples, statements claiming a rarity today of classic cases of parathyroid adenoma; frequent hypercalcemia in Hashimoto thyroiditis due to loss of calcitonin secretory activity; large supplies of calcitonin in the adrenal medulla; the association of sprains, varicose veins, hernias, hemorrhoids, clubbing, and congestive heart failure with primary hyperparathyroidism; a significant frequency of normocalcemic hyperparathyroidism; hypercalcemia in Cushing syndrome; and a "destiny" for patients with idiopathic hypoparathyroidism to develop Addison disease and/or pernicious anemia all go far beyond the actual facts. Further, the authors insist that a major action of parathyroid hormone is to produce adverse catabolic effects in all connective tissues

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