Dog kidneys perfused with either cryoprecipitated plasma or silica gel fraction for 24 hours had normal function posttransplantation. In the absence of warm ischemia, albumin was as good a perfusate as cryoprecipitated plasma and silica gel fraction. If the kidneys were ischemically damaged, perfusion with albumin and plasma protein fraction (Plasmanate) did not prevent poor kidney function after transplantation. However, all ischemically damaged kidneys perfused with cryoprecipitated plasma or silica gel fraction functioned normally after transplantation. Because silica gel fraction can be stored easily; it is easier to use as a perfusate than cryoprecipitated plasma.
Toledo-Pereyra LH, Condie RM, Callender CO, Mozes MF, Moberg AW, Santiago-Delpin EA, Simmons RL, Najarian JS. Hypothermic Pulsatile Kidney PreservationComparative Analysis of Plasma Fractions. Arch Surg. 1974;109(6):816-818. doi:10.1001/archsurg.1974.01360060082022