April 1975

Carcinoid Tumors With Supraclavicular-Lymph Node Metastasis

Author Affiliations

Durham, NC

Arch Surg. 1975;110(4):450. doi:10.1001/archsurg.1975.01360100092027

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To the Editor.—Welling and Taggart recently reported the first case of carcinoid tumor metastatic to the neck (Arch Surg 110:111, 1975). In the last four years we had the opportunity to evaluate 22 patients with carcinoid tumors. Although none of the 11 patients with nonserotonin-secreting carcinoid tumors had cervical node involvement, three of the 11 patients with serotonin-producing carcinoid tumors (and the carcinoid syndrome) had enlarged supraclavicular nodes.

A 53-year-old man developed melena and a left supraclavicular mass in 1963. Biopsy examination revealed that the mass was a Virchow node containing carcinoid tumor. The primary carcinoid tumor, located in the terminal ileum, was resected. In 1968 the patient developed the carcinoid syndrome. In 1972, during a laparotomy for recurrent gastrointestinal tract bleeding, hepatic metastases were noted. In 1974 the patient's liver function test results, liver size, and results of a liver scan (technetium Tc 99m sulfur colloid) remained within

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