August 1975

The Application of Ultrasound to the Study of Thyroid EnlargementManagement of 450 Cases

Author Affiliations

From the departments of surgery (Dr. Rosen), medicine (Dr. Walfish), and radiological sciences (Dr. Miskin), Mount Sinai Hospital and the University of Toronto Medical School, Toronto.

Arch Surg. 1975;110(8):940-944. doi:10.1001/archsurg.1975.01360140084017

Four hundred fifty cases of thyroid enlargement were studied by B-mode ultrasonography. Specific ultrasonographic patterns could be established for cyst, solid tumors, multinodular goiter, cystadenoma, and thyroiditis. Benign and malignant tissue could not be differentiated. In 155 cases, tissue diagnosis was established usually by operation but also by aspiration cytology. One hundred forty-two were hypofunctioning solitary nodules. The reliability of ultrasonographic diagnosis was 94%. It permitted safe aspiration of cysts, early operation of solid lesions, and avoidance of radiation hazard in the management of pregnant and pediatric patients. Our operative series showed the following incidences: cancer 16%, cyst 20%, and neoplasm 62%.