• The addition of a 0.45μ in-line membrane-filter to the delivery system for intra-arterial infusion therapy is a simple and inexpensive means of providing additional safety. The filter decreases particulate and microorganism infusion by removing all measurable particles and most bacterial and fungal organisms. Since air will not pass through the filter, air embolism is prevented. In addition, in the event of set disruption, the filter will prevent bleeding via red blood cells clogging the membrane.
(Arch Surg 111:201, 1976)
Meeker WR, Rapp RP, DeLuca PP, Bivins BA. Membrane FiltersAdditional Safety for Intra-arterial Infusions. Arch Surg. 1976;111(2):201. doi:10.1001/archsurg.1976.01360200107024