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April 1976

Surgical Treatment of Hepatic Metastases From Colorectal Cancers

Author Affiliations

From the departments of surgery, Mayo Clinic and Mayo Foundation (Dr Adson) and the Mayo Graduate School of Medicine, University of Minnesota (Dr Wilson), Rochester.

Arch Surg. 1976;111(4):330-334. doi:10.1001/archsurg.1976.01360220026004

• Follow-up data covering periods of two to 23 years have been collected on 60 patients who had resection of hepatic metastases for colorectal cancer. Multiple lesions were removed from 20 patients, and solitary lesions were excised from the other 40 patients.

Only one patient died during hospital convalescence. No patient who had multiple lesions excised lived for five years. In contrast, 15 of the 36 patients eligible for five-year survival study who had resection of apparent solitary lesions lived for five years or more, and eight patients were alive without evidence of recurrence ten years or more after operation.

These surprisingly favorable results of surgical treatment were analyzed in relation to results in patients who had biopsy specimens taken of lesions of comparable size and number, but no removal at the time of colonic resection. No patient in this control group lived for five years. Aggressive surgical treatment of apparent solitary hepatic metastatic lesions from colorectal cancer seems to be justified by the survival rate of surgically treated patients.

(Arch Surg 111:330-334, 1976)