July 1976

Osteolytic Lesion Indicating Pseudomonas Sternal Osteomyelitis

Author Affiliations

From the divisions of cardiothoracic surgery (Drs Mandal and Oparah) and infectious disease (Drs Fiala and Thadepalli), Charles R. Drew Postgraduate Medical School, and Los Angeles County-Martin Luther King, Jr, General Hospital, Los Angeles.

Arch Surg. 1976;111(7):776-778. doi:10.1001/archsurg.1976.01360250052010

• Two cases of osteolytic lesion of the sternum were caused by Pseudomonas aeruginosa. Both were in heroin addicts, and both occurred as a delayed reaction to injury in an automobile accident. Bony curettage and appropriate antibiotic therapy were sufficient for diagnosis and cure. Tobramycin sulfate (3 mg/kg/day), a new aminoglycoside, was successfully used in both instances. Excision of the sternum was not necessary.

(Arch Surg 111:776-778, 1976)