• It is generally accepted that we still lack a conclusive answer, to whether lowering of the lipid level will prevent the development or reverse the progression of coronary atherosclerosis. Multiple risk factor intervention trials now have the merit of addressing themselves to probable and practical needs for intervening on several of the major risk factors to obtain the maximum impact on populations at risk.
(Arch Surg 113:80-83, 1978)
Rifkind BM, Levy RI. Testing the Lipid HypothesisClinical Trials. Arch Surg. 1978;113(1):80–83. doi:10.1001/archsurg.1978.01370130082014