• Clindamycin penetrated extremely well into inflamed (19) and normal (one) appendices. Average levels in appendiceal tissue taken 26 to 300 minutes after a single intravenous dose were 154% of the simultaneous serum concentration.
(Arch Surg 113:1094-1095, 1978)
Berger SA, Barza M, Leslie SW, Raciti A, Kazarian KK, Kane A. Penetration of Clindamycin Into the Human Appendix. Arch Surg. 1978;113(9):1094-1095. doi:10.1001/archsurg.1978.01370210076010