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August 1980

Safety and Efficacy of a New Synthetic Burn DressingA Multicenter Study

Author Affiliations

From the Burn Center, Department of Surgery, Cornell Medical Center, New York (Drs Curreri and Desai); the Burn Center, Harborview Medical Center, University of Washington, Seattle (Dr Heimbach); the Burn Unit, Emanuel Hospital, Oregon Burn Center, Portland (Dr Parshley); the Burn Unit, San Francisco General Hospital (Dr Trunkey); and the Burn Unit, University of California at Irvine (Dr Bartlett).

Arch Surg. 1980;115(8):925-927. doi:10.1001/archsurg.1980.01380080021004

• A three-tiered, multicenter study evaluated the safety and efficacy of a new synthetic dressing for burn injuries. The first tier compared use of the test dressing with use of a conventional topical chemotherapeutic agent; the test dressing afforded greater patient comfort, equivalent control of bacterial growth, less frequent dressing change, and possibly faster reepithelialization. Drawbacks included difficulty of application, poor adherence during the first 24 hours after injury, frequent necessity to repair cracks and fissures, and inability to easily monitor burn wounds for bacterial growth. Subsequent tiers were noncomparative but included patients with more severe injuries. The test dressing may be useful in treating superficial and moderate second-degree burns of less than 20% of the total body surface area and possibly in treating iatrogenic "burn" wounds such as donor sites. Its use on third-degree burns is not recommended.

(Arch Surg 115:925-927, 1980)