• Pseudoxanthoma elasticum and polyposis coli are inherited conditions not, to our knowledge, previously reported to coexist. The spontaneous appearance of both conditions in a 62-year-old woman may represent a novel mutation. The defective cell in both pseudoxanthoma and some of the extracolonic manifestations of Gardner's syndrome is the fibroblast; therefore, this case may represent a unique variation of Gardner's syndrome.
(Arch Surg 1981;116:476-477)
O'Holleran M, Merrell RC. Pseudoxanthoma Elasticum and Polyposis ColiA Novel Co-mutation. Arch Surg. 1981;116(4):476-477. doi:10.1001/archsurg.1981.01380160086019