• A left atrial—femoral artery (LA-FA) bypass system was designed to deliver synchronous pulsatile blood flow. We compared it with nonpulsatile LA-FA bypass in its effectiveness to limit infarct extension after ligation of the left anterior descending coronary artery at its origin in 35 dogs. Nonpulsatile LA-FA bypass resulted in a 70% reduction in the size of infarct. The addition of synchronous diastolic counterpulsation (P—LA-FA) further reduced the size of infarct, when compared with that in controls (95%) or animals that underwent LA-FA bypass (83%). Both LA-FA and P—LA-FA bypasses limited infarct extension and reduced mortality after acute coronary occlusion through effective unloading of the left ventricle. The addition of diastolic counterpulsation to LA-FA bypass led to further significant infarct reduction, when compared with LA-FA bypass alone. These effects were most likely secondary to improvements in myocardial blood flow distribution.
(Arch Surg 1983;118:965-969)
Laschinger JC, Cunningham JN, Catinella FP, Knopp EA, Glassman E, Spencer FC. 'Pulsatile' Left Atrial-Femoral Artery BypassA New Method of Preventing Extension of Myocardial Infarction. Arch Surg. 1983;118(8):965-969. doi:10.1001/archsurg.1983.01390080067017