• We followed up 133 patients with claudication to determine the prognostic value of dependent rubor. Life tables analysis was used, with a threatened limb as the endpoint. A threatened limb was defined as the development of ischemic rest pain, skin ulceration, or gangrene. At four years, the rubor group had a limb-threat incidence of 25%, compared with only 9% in the nonrubor group. While not indicative of imminent limb loss, the presence of dependent rubor defines patients whose limb risk is greater than in those with claudication alone.
(Arch Surg 1984;119:932-935)
Kozol RA, Bredenberg CE, Fey JD, Oates RP. Dependent Rubor as a Predictor of Limb Risk in Patients With Claudication. Arch Surg. 1984;119(8):932-935. doi:10.1001/archsurg.1984.01390200050012