October 1984

A Clinical Technique for Prevention of Spasm and Preservation of Endothelium in Saphenous Vein Grafts

Author Affiliations

From Vascular Dynamics Laboratory, Department of Surgery, University Hospital (Drs LoGerfo and Mr Quist) and the Mallory Institute of Pathology (Dr Haudenschild), Boston University Medical Center.

Arch Surg. 1984;119(10):1212-1214. doi:10.1001/archsurg.1984.01390220086020

• Spasm and endothelial injury during harvesting of saphenous vein grafts can be prevented by a protocol that involves perivenous infiltration with 37 °C papaverine hydrochloride solution prior to skin incision, initial distention of the vein with the same warm papaverine solution, storage of the distended vein graft in a cold papaverine solution, and maintenance of the vein in the distended state throughout the operative procedure. This technique preserves endothelial integrity In human reversed saphenous vein grafts.

(Arch Surg 1984;119:1212-1214)