• Spasm and endothelial injury during harvesting of saphenous vein grafts can be prevented by a protocol that involves perivenous infiltration with 37 °C papaverine hydrochloride solution prior to skin incision, initial distention of the vein with the same warm papaverine solution, storage of the distended vein graft in a cold papaverine solution, and maintenance of the vein in the distended state throughout the operative procedure. This technique preserves endothelial integrity In human reversed saphenous vein grafts.
(Arch Surg 1984;119:1212-1214)
LoGerfo FW, Haudenschild CC, Quist WC. A Clinical Technique for Prevention of Spasm and Preservation of Endothelium in Saphenous Vein Grafts. Arch Surg. 1984;119(10):1212-1214. doi:10.1001/archsurg.1984.01390220086020