July 1986

Long-Acting β-Adrenergic Antagonists as Preparation for Surgery in Thyrotoxicosis

Author Affiliations

From the Departments of Surgery (Drs Gerst and Fildes) and Medicine (Drs Baylor and Zonszein), The Bronx-Lebanon Hospital Center, New York.

Arch Surg. 1986;121(7):838-840. doi:10.1001/archsurg.1986.01400070108022

• This report describes our experience with 12 patients with thyrotoxic Graves' disease who were prepared for thyroidectomy using only a long-acting orally administered β-adrenergic blocking agent (nadolol or atenolol); iodides were not used. This form of preparation proved to be very effective, fast acting, and economical. It permitted rapid preparation of patients for surgery and resulted in excellent control of the manifestations of hyperthyroidism in the perioperative period. The surgery was relatively easy and bloodless, and there were no operative complications. We recommend that these longacting β-adrenergic blocking agents be considered as the preferred medication for the preparation of thyrotoxic patients for surgery.

(Arch Surg 1986;121:838-840)