• Glucagon use as a muscle relaxant is common in radiologic and endoscopic examinations in which smooth-muscle spasm has interfered. Glucagon also provokes catecholamine release from an unsuspected pheochromocytoma, as occurred in a 60-year-old patient undergoing biliary tract surgery. To prevent hypertensive crisis and ventricular tachyarrhythmia after intraoperative glucagon administration, appropriate pharmacologic catecholamine antagonists must be immediately available.
(Arch Surg 1987;122:833-834)
Schorr RT, Rogers SN. Intraoperative Cardiovascular Crisis Caused by Glucagon. Arch Surg. 1987;122(7):833-834. doi:10.1001/archsurg.1987.01400190099022