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July 1987

Intraoperative Cardiovascular Crisis Caused by Glucagon

Author Affiliations

From the Departments of Surgery (Dr Schorr) and Anesthesia (Dr Rogers), Grossmont Hospital, La Mesa, Calif.

Arch Surg. 1987;122(7):833-834. doi:10.1001/archsurg.1987.01400190099022

• Glucagon use as a muscle relaxant is common in radiologic and endoscopic examinations in which smooth-muscle spasm has interfered. Glucagon also provokes catecholamine release from an unsuspected pheochromocytoma, as occurred in a 60-year-old patient undergoing biliary tract surgery. To prevent hypertensive crisis and ventricular tachyarrhythmia after intraoperative glucagon administration, appropriate pharmacologic catecholamine antagonists must be immediately available.

(Arch Surg 1987;122:833-834)