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Original Article
August 1987

Cryptogenic Abscess of the LiverEvidence of Underlying Reticuloendothelial Cell Dysfunction

Author Affiliations

From the Department of Medicine, University of Calgary, Calgary, Alberta.

Arch Surg. 1987;122(8):906-908. doi:10.1001/archsurg.1987.01400200056009

• Evidence of underlying liver disease and reticuloendothelial system dysfunction was sought in five adults with histories of idiopathic or "cryptogenic" liver abscess. Although no evidence of underlying liver disease was obtained (median follow-up, 3.4 years; range, 2.1 to 4.8 years), four of five individuals demonstrated a marked impairment in their ability to clear antibody-tagged erythrocytes from the systemic circulation. The results of this study suggest that patients who develop cryptogenic abscesses of the liver have an underlying reticuloendothelial cell defect that may predispose them to liver abscess formation.

(Arch Surg 1987;122:906-908)