March 1991

Cytologic Diagnosis of Aspergillosis in Cardiac Transplantation

Author Affiliations

From the Department of Pathology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC (Drs McCalmont and Geisinger), and the Department of Clinical Pathology and Diagnostic Medicine, East Carolina University School of Medicine, Greenville (Dr Silverman). Dr McCalmont is now with the University of California, San Francisco.

Arch Surg. 1991;126(3):394-396. doi:10.1001/archsurg.1991.01410270144022

• Fine-needle aspiration of the lung is now widely utilized to diagnose pulmonary neoplasms, but often serologic techniques or open-lung biopsy is relied on for the diagnosis of infectious pulmonary processes. We report a series of four patients in whom the fine-needle aspiration technique was used to make the rapid cytologic diagnosis of pulmonary aspergillosis. Culture confirmation was also obtained on the aspirated material. A discussion of the available techniques for the laboratory diagnosis of pulmonary aspergillosis is presented and the advantages of fine-needle aspiration cytology are stressed. Our favorable results support expanded use of fine-needle aspiration cytology in the evaluation of lung nodules appearing in immunosuppressed populations.

(Arch Surg. 1991;126:394-396)