• In 193 gastric resections for adenocarcinoma, lymphadenectomy was prospectively evaluated to quantify the number of lymph nodes and to identify prognostic factors. Overall, 7112 nodes (median, 36.8 per patient) were resected with 27.2% showing metastases. Most nodes were found in the perigastric region. The histologic type and site of the tumor did not influence the number of invaded nodes, but tumor stage and quality of the resection (curative/palliative) did. By multivariate analysis the tumor stage, curative vs palliative resections, and the number of metastatic lymph nodes in curative resections were independent prognostic factors. Patients with less than six metastatic nodes showed a survival not significantly different from that of patients with normal nodes. These patients may be well treated by surgery alone, but the other patients may require multimodal therapy to improve their prognosis.
(Arch Surg. 1992;127:290-294)
Jaehne J, Meyer H, Maschek H, Geerlings H, Bruns E, Pichlmayr R. Lymphadenectomy in Gastric CarcinomaA Prospective and Prognostic Study. Arch Surg. 1992;127(3):290-294. doi:10.1001/archsurg.1992.01420030052010