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April 1992

Graft Involvement by Legionella in a Liver Transplant Recipient

Author Affiliations

From the California Pacific Medical Center Transplant Services (Drs Tokunaga, Concepcion, Itasaka, Nakazato, and Esquivel), and the Departments of Pediatrics (Drs Berquist and Cox), Infectious Disease (Dr Wiviott), and Pathology (Dr Garcia-Kennedy), Pacific Presbyterian Medical Center, San Francisco, Calif.

Arch Surg. 1992;127(4):475-477. doi:10.1001/archsurg.1992.01420040121021

Legionella pneumophila, serogroup 1, was identified by direct immunofluorescence in the lung and liver graft from a 2½-month-old infant who underwent orthotopic liver transplantation because of fulminant hepatic failure secondary to neonatal hepatitis. The patient died of respiratory failure owing to this infection 22 days after transplantation despite treatment with erythromycin lactobionate. To our knowledge, this represents the first reported case of hepatic infection with Legionella in liver transplant recipients.

(Arch Surg. 1992;127:475-477)