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In Reply.—In our studies involving antineutrophil serum, proteinase inhibitors, and oxygen free radical scavengers, we have primarily been interested in the effects of these substances on intestinal wound margin strength. We have not attempted to quantify the formation of peritoneal adhesions in these experiments, and therefore have no available data on that issue. The concept that oxygen free radicals might induce adhesion formation is challenging. However, to our knowledge, the hypothesis remains to be tested in an experimental setting.
JONSSON T, HÖGSTRÖM H. Neutrophilia, Oxygen Free Radicals, and Abdominal Adhesions-Reply. Arch Surg. 1992;127(6):747. doi:10.1001/archsurg.1992.01420060127022