October 1994

Surgery: Scientific Principles and Practice

Author Affiliations

Minneapolis, Minn


edited by Lazar J. Greenfield, Michael W. Mullholland, Keith T. Oldham, and Gerald B. Zelenock, 2179 pp, $110, Philadelphia, Pa, JB Lippincott Co, 1993.

Arch Surg. 1994;129(10):1106. doi:10.1001/archsurg.1994.01420340120027

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This is a big book in two parts. It equals the 2000-page size of the other monster general surgical texts. The editors have produced a very good book with an innovative emphasis on the fundamental biologic processes that underlie surgical disease states. There has been an explosion of knowledge in molecular and cellular biology, immunology, and genetics. This has allowed surgical researchers to apply quantifiable processes to surgical problems in altered metabolism, immune response, shock, and multiple system impairment after injury or infection. The requisite science is complex and scattered throughout multiple scientific disciplines. It is not a trivial effort for an interested surgeon to find the time to organize, understand, and distill the essence of interrelated cellular processes.

The first section of this book, "Scientific Principles," squarely meets the challenge. These first 571 pages are well worth the price of the book. Even this condensed form of surgical basic

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