February 1997

Interleukin-6 and a Delay of Neutrophil Apoptosis After Major Surgery

Author Affiliations

From the Department of Clinical Pharmacology, Jichi Medical School, Tochigi, Japan.

Arch Surg. 1997;132(2):209-210. doi:10.1001/archsurg.1997.01430260107023

Surgical treatments affect host immune systems. Apoptosis of the circulatory lymphocytes and an elevation of the number of neutrophils are induced by surgery. These alterations are not dependent only on the stress hormone. The course of neutrophilia and the serum concentration of interleukin-6 are given after various surgical treatments. Neutrophil-mediated lung injury is discussed.

Arch Surg. 1997;132:209-210