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March 1967

Parathyroid CystsReport of Two Cases and a Review of the Literature

Author Affiliations

From the Department of Surgery, Northwestern University Medical School, Chicago.

Arch Surg. 1967;94(3):421-426. doi:10.1001/archsurg.1967.01330090115027

PARATHYROID cysts are an uncommon cause of masses in the neck, which require surgical intervention. Since Goris1 described the first case in 1905, only 56 have been reported in the world literature to date2-28 (Table). In the surgical experience of the Northwestern University Medical Center, four clinically apparent parathyroid cysts have been diagnosed and excised, two of which have been previously reported.17 This paper will report two additional cases, as well as summarize the pertinent data of this unusual lesion and review the literature.

Report of Cases 

Case 1.  —A 68-year-old white woman was first admitted to Chicago Wesley Memorial Hospital on Nov 4, 1964. She had noticed a "lump in her neck" while looking in the mirror five months prior to admission. She consulted her physician who told her that she had a nodule in her thyroid gland. Since that time, she had noted an intermittent,

Goris:  Extirpation de trois lobules parathyroidiens kystiques , J Chir Ann Pa Soc Belge Chir 5:394, 1905.
Anzilotti, G.:  Contributo alla patogenesi delle cisti parabranchiali del collo: Ciste del ductus parathyroidens , Clin Chir 17:610, 1909.
De Quervain, F.:  Chirurgishe Demonstrationen. (Epithel-Korperchen-Cysti) , Schweiz Med Wschr 55:1168, 1925.
Nylander, P.E.A.:  Uber parathyreoideale hahzysten , Acta Chir Scand 64:539, 1929.
McKnight, R.B.:  Parathyroid Cyst , Southern Surg 12:179, 1946.
Welti, H.:  Apropos des kystes parathyroidiens , Mem Acad Chir 72:33, 1946.
Black, B.M., and Watts, CF.:  Cysts of Parathyroid Origin: Report of Two Cases and Study of the Incidence and Pathogenesis of Cysts in Parathyroid Glands , Surgery 25:941, 1949.
McGoon, D.C., and Cooley, D.A.:  Parathyroid Cyst: An Unusual Cervical Tumor; Report of Three Cases , Surgery 30:725, 1951.
Greene, E.I.; Greene, J.M.; and Busch, R.C.:  Unusual Manifestations After Removal of a Parathyroid Cyst , JAMA 150:853, 1952.Article
Maxwell, D.B.; Horn, R.C.; and Rhoads, J.E.:  Cysts of the Parathyroid: Report of Three Cases Clinically Simulating Nodular Goiter , Arch Surg 64:208, 1952.Article
Crile, G., Jr., and Perryman R.G.:  Parathyroid Cysts: Report of Five Cases , Surgery 34:151, 1953.
Keynes, W.M., and Truscott, B.McN.:  Large Solitary Cysts of the Parathyroid Gland , Brit J Surg 44( (183) ):23, 1956.Article
Welti, H., and Gerard-Marchant, R.:  Apropos de cinq nouvelles observation de kystes parathyroidien , Mem Acad Chir 82:994, 1956.
Fisher, E.R., and Gruhn, J.:  Parathyroid Cysts , Cancer 10:57, 1957.Article
Perdue, G.D., and Martin, J.D.:  Parathyroid Cysts: Report of a Case , Amer Surg 25:697, 1959.
Malkin, M., and Chapman, I.:  Parathyroid Cysts: A Problem in Differential Diagnosis , Oral Surg 14:8, 1961.Article
Shields, T.W., and Staley, C.J.:  Functioning Parathyroid Cysts , Arch Surg 82:937, 1961.Article
Beahrs, O.H., and Devine, K.D.:  Unusual Diagnostic Problems in the Neck , Surg Clin N Amer 41( (4) ):1069, 1961.
Jonassen, O.T.:  Parathyroid Cysts of Clinical Significance , Arch Surg 83:758, 1961.Article
Arnaud, CD.; Walker, J.A.; and Ewer, R.W.:  Primary Hyperparathyroidism Associated With a Cystic Lesion in the Neck: Probable Parathyroid Cyst , J Clin Endocr 21:833, 1961.Article
Kamegaya, K., and Mori, K.:  Parathyroid Cyst and Multicystic Parathyroid Adenoma , Acta Path Jap 12:99, 1962.
Rosenbaum, G.R., and Morad, A.:  A Review of Parathyroid Cysts , W Virginia Med J 59:300, 1963.
McGinty, C.P., and Lischer, C.E.:  The Surgical Significance of Parathyroid Cysts , Surg Gynec Obstet 117:703, 1963.
Lohrenz, F.N., and Neubecker, R.D.:  Parathyroid Cyst Presenting as an Enlarging Cervical Nodule , Wisconsin Med J 63:123, 1964.
Weeks, P.M.:  Clinically Significant Parathyroid Cysts , Amer Surg 31:366, 1965.
Fratkin, L.B.:  Parathyroid Cyst: Report of Four Cases , Amer Surg 31:420, 1965.
Gitlitz, B.:  The Parathyroid Cyst , Rocky Mountain Med J 62:38, 1965.
Gordon, A., and Harcourt-Webster, J.N.:  Parathyroid Cysts: A Report of Two Cases , J Path Bact 89:374, 1965.Article
Castleman, B., and Mallory, T.B.:  The Pathology of the Parathyroid Gland in Hyperparathyroidism , Amer J Path 11:1, 1935.
Gilmour, J.R.:  The Embryology of the Parathyroid Glands, the Thymus, and Certain Associated Rudiments , J Path Bact 45:507, 1937.Article
Gilmour, J.R.:  The Normal Histology of the Parathyroid Glands , J Path Bact 48:187, 1939.Article
Selye, H.; Ortega, M.R.; and Tuchweber, B.:  Experimental Production of Parathyroid Cysts , Amer J Path 45:251, 1964.