[Skip to Content]
Sign In
Individual Sign In
Create an Account
Institutional Sign In
OpenAthens Shibboleth
[Skip to Content Landing]
February 1972

Impedance Measurement in the Diagnosis of Deep Venous Thrombosis

Author Affiliations

From the departments of surgery (Drs. Dmochowski and Couch) and radiology (Dr. Adams), Peter Bent Brigham Hospital, Boston.

Arch Surg. 1972;104(2):170-173. doi:10.1001/archsurg.1972.04180020050009

Impedance measurements were conducted on 50 limbs of 25 normal subjects, and on 43 limbs of 24 patients with clinical suspicion of deep venous thrombosis. On all patients, the impedance studies were followed by a phlebogram. Thirty-four out of 50 normal limbs showed a reduction of impedance during deep inspiration of more than 0.2%. The remaining 16 limbs demonstrated an impedance deflection of less than 0.2%. In patients, there were six false positive results, and one false negative result. Using the method described, it was concluded that the overall accuracy of impedance testing for diagnosing presence or absence of recent clots was 53.5%. Nevertheless, impedance measurement is a useful screening procedure for detection of deep thrombophlebitic disease of the lower extremity if its limitations are taken into account, primarily because of the very low rate of "false negative" results.

Kakkar VV:  The problems of thrombosis in the deep veins of the leg . Ann Roy Coll Surg Eng 45:257-276, 1969.
Kakkar VV, Howe CT, Nicolaides AN, et al:  Deep vein thrombosis of the leg: Is there a "high risk" group? Amer J Surg 120:527-530, 1970.Article
Coon WW, Willis PW III:  Deep venous thrombosis and pulmonary embolism: Prediction, prevention and treatment . Amer J Cardiol 4:611-621, 1959.Article
Breneman JC:  Postoperative thromboembolic disease: Computer analysis leading to statistical prediction . JAMA 193:576-580, 1965.Article
DeBakey MD:  Collective review: Critical evaluation of the problem of thromboembolism . Surg Gynec Obstet 98:1-27, 1954.
Mullick SC, Wheeler HB, Songster GP:  Diagnosis of deep venous thrombosis by measurement of electrical impedance . Amer J Surg 119:417-422, 1970.Article
Wheeler HB, Mullick SC, Anderson JN, Pearson D:  Diagnosis of occult deep vein thrombosis by a noninvasive bedside technique . Surgery 70:20-28, 1971.
Couch NP, Van De Water JM, Dmochowski JR:  Noninvasive measurement of peripheral arterial flow: Impedance cardiograph and ultrasonic Doppler flowmeter . Arch Surg 102:435-439, 1971.Article