Unselected cholecystectomy specimens in Honolulu had positive bacterial cultures in 46.7% of 501 cases. The numbers were much greater in acute cholecystitis, in ductal obstruction, and in elderly patients. The most commonly cultured organisms were Escherichia coli, Klebsiella-Enterobacter, enterococci, Clostridium perfringens, and staphylococci. Gallstones did not influence the prevalence of positive cultures. Wound infections occurred in 11% of the men and 2% of the women. The same organism was cultured from both the wound and the gallbladder in 65% of the cases. In most of the cases where the bacteria in the wound and gallbladder differed, another organ was also removed. Gallbladder culture is a useful tool in the prophylaxis and management of wound infections. This is especially true in elderly patients, in acute cholecystitis, and with ductal obstruction.
Fukunaga FH. Gallbladder Bacteriology, Histology, and GallstonesStudy of Unselected Cholecystectomy Specimens in Honolulu. Arch Surg. 1973;106(2):169-171. doi:10.1001/archsurg.1973.01350140033011