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February 1973

Gallbladder Bacteriology, Histology, and GallstonesStudy of Unselected Cholecystectomy Specimens in Honolulu

Author Affiliations

From the Department of Pathology, Kuakini Hospital, Honolulu.

Arch Surg. 1973;106(2):169-171. doi:10.1001/archsurg.1973.01350140033011

Unselected cholecystectomy specimens in Honolulu had positive bacterial cultures in 46.7% of 501 cases. The numbers were much greater in acute cholecystitis, in ductal obstruction, and in elderly patients. The most commonly cultured organisms were Escherichia coli, Klebsiella-Enterobacter, enterococci, Clostridium perfringens, and staphylococci. Gallstones did not influence the prevalence of positive cultures. Wound infections occurred in 11% of the men and 2% of the women. The same organism was cultured from both the wound and the gallbladder in 65% of the cases. In most of the cases where the bacteria in the wound and gallbladder differed, another organ was also removed. Gallbladder culture is a useful tool in the prophylaxis and management of wound infections. This is especially true in elderly patients, in acute cholecystitis, and with ductal obstruction.

Gordon-Taylor G, Whitby LEH:  Bacteriological study of 50 cases of cholecystectomy with special reference to anaerobic infections . Br J Surg 18:78-83, 1930.Article
Gordon-Taylor G, Whitby LEH:  The incidence of anaerobic infections in the gallbladder . Br J Surg 19:619-621, 1932.Article
Sarmiento RV:  Emphysematous cholecystitis . Arch Surg 93:1009-1014, 1966.Article
Marshall JF, Hartzog DC:  Acute emphysematous cholecystitis . Ann Surg 159:1011-1016, 1964.Article
Flemma RJ, et al:  Bacteriologic studies of biliary tract infections . Ann Surg 166:563-572, 1967.Article
Mason GR:  Bacteriology and antibiotic selection in biliary tract surgery . Arch Surg 97:533-537, 1968.Article
Andrews E, Henry LD:  Bacteriology of normal and diseased gallbladders . Arch Intern Med 56:1171-1188, 1935.Article
Womack NA, Bricker EM:  Pathogenesis of cholecystitis . Arch Surg 44:658-676, 1942.Article
Robson MC, Bogart JN, Heggers JP:  An endogenous source of wound infections based on quantitative bacteriology of the biliary tract . Surgery 86:471-476, 1970.
Howe CW:  Experimental wound sepsis from transient bacteremia . Surg Gynecol Obstet 126:1066-1070, 1968.