[Skip to Content]
Sign In
Individual Sign In
Create an Account
Institutional Sign In
OpenAthens Shibboleth
[Skip to Content Landing]
January 1974

"Spontaneous" Rupture of Homografted Kidneys

Author Affiliations

Groningen, the Netherlands
From the departments of general surgery, urology, medicine, and pathology, University Hospital, Groningen, the Netherlands.

Arch Surg. 1974;108(1):107-112. doi:10.1001/archsurg.1974.01350250093025

Two patients had ruptures of homografted kidneys; in one the kidney had to be removed; in the other the bleeding was so severe that the patient died within minutes. The clinical picture is described, a hypothesis of the mechanism of the rupture is discussed, and an outline of the treatment is given. The incidence of rejection in all histologically examined ruptured kidneys and the plausible mechanism of rupturing during rejection has led us to the conclusion that a rupture of a homografted kidney is not a spontaneous event, but a complication of rejection.

Gellei B, et al:  Polymorphonuclear leukocyte count in immediate biopsy of cadaver kidney grafts . Arch Pathol 92:98-100, 1971.
Kincaid-Smith P, et al:  Immediate renal-graft biopsy and subsequent rejection . Lancet 2:748-749, 1968.Article
Murray JE, et al:  Five years' experience in renal transplantation with immunosuppressive drugs: Survival, function, complications, and the role of lymphocyte depletion by thoracic duct fistula . Ann Surg 168:416-435, 1968.Article
Siedek M:  Beobachtungen bei Rejektion von Nierentransplantaten . Langenbecks Arch Chir 325:714-719, 1969.Article
Lord RS, et al:  Delayed spontaneous rupture of the allografted kidney . Arch Surg 100:607-610, 1970.Article
Flanigan WJ, et al:  Clinical patterns of renal allograft rejection . Ann Surg 173:733-747, 1971.Article
Haimov M, et al:  Spontaneous rupture of the allografted kidney . Arch Surg 103:510-512, 1971.Article
Minale C, et al:  Spontanruptur von Nierentransplantaten . Dtsch Med Wochenschr 97:459-461, 1972.Article
Lord RSA, et al:  Renal allograft rupture: Cause, clinical features, and management . Ann Surg 177:268-273, 1973.Article
Rosen SM, et al:  Intrarenal distribution of blood flow in the transplanted dog kidney: Effect of denervation and rejection . J Clin Invest 44:1239-1253, 1967.Article
Donker AJM:  Filtration fraction and rejection , abstracted. Folia Med Neerl 15:311, 1972.
Kountz SL, et al:  Serial hemodynamics after renal allotransplantation in man . Circulation 41:217-224, 1970.Article
Silcott GR, et al:  Functional recovery from acute rejection as a guide to ultimate renal graft survival . Arch Surg 104:791-793, 1972.Article