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Article
April 1974

Recurrent Pheochromocytoma

Author Affiliations

Ann Arbor, Mich
From the departments of surgery (Drs. Harrison and Freier) and internal medicine (Dr. Cohen), the University of Michigan Medical Center, Ann Arbor.

Arch Surg. 1974;108(4):450-454. doi:10.1001/archsurg.1974.01350280056010
Abstract

Seven of 28 patients had well-established recurrent disease following a primary operation for control of pheochromocytoma. Two of these recurrences were in 23 patients whose primary operation had been performed by us. The other five were referred to us with recurrent pheochromocytoma.

A broad range of pathologic entities is represented in these patients. One patient had an asymptomatic biochemical recurrence of disease and one multiple benign primary pheochromocytoma. A third had a local recurrence with negative lymph nodes and a fourth focal lymph node recurrences. Long-term resolution of disease has occurred in three of these patients following another exploratory operation.

Three patients had disseminated disease, one had abdominal recurrences, and two had miliary pulmonary disease that escaped pre-operative detection on conventional posteroanterior roentgenographic views of the chest. The latter two patients died after fruitless surgical exploration and represent the only deaths in our series.

References
1.
Harrison TS, Bartlett JD Jr, Seaton JF:  Current evaluation and management of pheochromocytoma . Ann Surg 168:701-713, 1968.Article
2.
Hume DM:  Pheochromocytoma in the adult and child . Am J Surg 99:458-496, 1960.Article
3.
Priestly JT, Kvale WF, Gifford RW:  Pheochromocytoma: Clinical aspects and surgical treatment . Arch Surg 86:778-790, 1963.Article
4.
Sjoerdsma A, Engelmann I, Waldmann WG:  Pheochromocytoma: Current concepts of diagnosis and treatment . Ann Intern Med 65:1302-1326, 1966.Article
5.
Scott HW, Riddell DH, Brockman SK:  Surgical management of pheochromocytoma . Surg Gynecol Obstet 120:702-724, 1965.
6.
Harrison TS, Birbari A, Seaton JF:  Malignant hypertension in pheochromocytoma . Johns Hopkins Med J 130:329-332, 1972.
7.
Jaffe RB, Harrison TS, Cerny JC:  Localization of metastatic pheochromocytoma in pregnancy by caval catheterization, including urinary catecholamine values in uncomplicated pregnancies . Am J Obstet Gynecol 104:939-944, 1969.
8.
Harrison TS, Freier DT: Pitfalls in the technique and interpretation of regional venous sampling for localizing pheochromocytoma. Surg Clin North Am, to be published.
9.
Harrison TS, et al:  Rationale and indications for preoperative adrenergic receptor blockade in pheochromocytoma . Med Clin North Am 53:1349-1358, 1969.
10.
Anderson BG, et al:  Labeled dopamine concentration in pheochromocytoma . J Nucl Med , 14:781-784, 1973.
11.
Sellwood RA, et al:  Recurrent pheochromocytoma . Br J Surg 57:309-312, 1970.Article
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