[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
Sign In
Individual Sign In
Create an Account
Institutional Sign In
OpenAthens Shibboleth
[Skip to Content Landing]
January 1975

Carcinoid Tumor Metastatic to Neck

Author Affiliations

From the US Naval Hospital, Orlando, Fla. Dr. Welling is now with the Department of Surgery, Good Samaritan Hospital, Cincinnati.

Arch Surg. 1975;110(1):111-113. doi:10.1001/archsurg.1975.01360070111018

A 50-year-old woman was admitted with a mass in the anterior triangle of the neck. Because of interpretation of a needle biopsy specimen as undifferentiated adenocarcinoma, a radical excision of cervical lymph nodes was performed and the specimen showed metastatic adenocarcinoma suggestive of carcinoid tumor. Four months later the patient developed an abdominal mass that turned out to be large mesenteric lymph nodes involved in carcinoid tumor, the primary lesions being in the terminal ileum. Following resection of all visible tumor, the patient has remained symptomatically and chemically well for 15 months. No previous case of carcinoid tumor metastatic to the neck can be found.

Merling, cited by Forbus WD:  Argentaffine tumors of the appendix and small intestine . Bull Johns Hopkins Hosp 37:130-153, 1925.
Langhans T:  Ueber einen Drüsenpolyp im Ileum . Virchows Arch 38:559-560, 1867.Article
Beger A:  Ein Fall von Krebs des Wurmfortsatzes . Klin Wochenschr 19:616-618, 1882.
Thorson A, Biörck G, Björkman G, et al:  Malignant carcinoid of the small intestine with metastases to the liver, valvular disease of the right side of the heart, peripheral vasomotor symptoms, bronchoconstriction, and an unusual type of cyanosis . Am Heart J 47:795-817, 1954.Article
Isler P, Hedinger C:  Metastasierendes Dünndarmcarcinoid mit schweren, vorwiegend das rechte Herz betreffend Klappenfehlern und Pulmonalstenose: Ein eigenartiger Symptomenkomplex? Schweiz Med Wochenschr 83:4-7, 1953.
Rosenbaum FF, Santer DG, Claudon DB:  Essential telangiectasia, pulmonary stenosis and neoplastic liver disease: A possible new clinical syndrome . J Lab Clin Med 42:941-942, 1953.
Sjoerdsma A, Oates JA, Zaltzman P, et al:  Serotonin synthesis in carcinoid patients: Its inhibition by alpha-methyl-dopa, with measurement of associated increases in urinary 5-hydroxytryptophan . N Engl J Med 263:585-588, 1960.Article
Sjoerdsma A, Weissbach H, Udenfriend S:  Simple test for diagnosis of metastatic carcinoid (argentaffinoma), correspondence . JAMA 159:397, 1955.Article
Gold IR, Grayziel DM:  Multiple argentaffinomas of the ileum with metastases in the lymph nodes and in the liver . Am J Surg 60:144-148, 1943.Article
Sanders RJ, Axtell HK:  Carcinoids of the gastrointestinal tract . Surg Gynecol Obstet 119:369-380, 1964.
Teitelbaum SL:  The carcinoid: A collective review . Am J Surg 123:564-572, 1972.Article
Moertel CG, Sauer WG, Dockerty MB, et al:  Life history of the carcinoid tumor of the small intestine . Cancer 14:901-912, 1961.Article
Shuster M, Mendoza-Divino E, Joselson H:  Carcinoid tumor metastasizing to the ovaries . Obstet Gynecol 36:515-519, 1970.
O'Brien JR:  Multiple argentaffinomata of the ileum revealed by secondary growth in the epididymis . Br Med J 2:1315-1316, 1951.Article
Dick A, Melrose AG, Sillar W, et al:  Carcinoid tumor with skeletal metastases . J R Coll Surg Edinb 2:209-215, 1957.
Norman JL, Cunningham PJ, Cleveland BR:  Skin and subcutaneous metastases from gastrointestinal carcinoid tumors . Arch Surg 103:767-769, 1971.Article
Dickson JA, Parkhill EM, Kiernan PC:  Large retroperitoneal metastasis from so-called carcinoid of the small intestine . Surg Gynecol Obstet 82:675-681, 1946.
Turner M, Gallager HS:  Occult appendiceal carcinoid . Arch Pathol 88:188-190, 1969.
Wilson H, Cheek RC, Sherman RT, et al: Carcinoid tumors. Curr Probi Surg , (November) 1970, pp 1-51.
Kerth JD, Sisson GA, Becker GD:  Radical neck dissection in carcinoma of the head and neck . Surg Clin North Am 53:179-190, 1973.