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February 1976

The Angiographic Evaluation of Human Renal AllotransplantsFunctional Graft Deterioration and Hypertension

Author Affiliations

From the departments of radiology (Dr Beachley) and surgery (Drs Pierce and Lee and Mr Boykin), the Virginia Commonwealth University/Medical College of Virginia, Richmond.

Arch Surg. 1976;111(2):134-142. doi:10.1001/archsurg.1976.01360200040007

• The renal arteriogram is a highly reliable test in the differential diagnosis of early transplant anuria, graft rejection, and hypertension. The reliability of the renal arteriogram was 97.8% in either substantiating or disproving the presence of a suspected episode of graft rejection or renal artery stenosis.

The earliest signs of acute humoral and acute rejection were a prolongation of arterial clearance time, diffuse edema with enlargement of the kidney, and progressive deterioration of the nephrogram.

Renal artery stenosis may be a sharply localized septum or an elongated narrowing at or distal to the actual site of anastomosis. This was seen primarily in patients' arteriograms more than 60 days after transplantation, and it is important because it is a surgically correctable cause of hypertension.

(Arch Surg 111:134-142, 1976)

Merrill JP:  Diagnosis and management of rejection in allografted kidneys . Transplant Proc 3:287-292, 1971.
Seldinger SL:  Catheter replacement of the needle in percutaneous arteriography: A new technique . Acta Radiol 39:368-376, 1953.Article
Vinik M, Smellie WAB, Freed TA, et al:  Angiographic evaluation of the human homotransplant kidney . Radiology 92:873-879, 1969.Article
O'Connor JF, Couch NP, Lindquist R, et al:  A correlation of arteriography, histology, and clinical course in kidney transplantation . Ann NY Acad Sci 129:637-653, 1966.Article
Vinik M, Smellie WAB, Freed TA, et al:  Renal ischemia and homograft rejection: Preliminary angiographic data in the dog . Invest Radiol 4:252-263, 1969.Article
Braun WE:  The renal-allograft bruit as an indicator of good function . N Engl J Med 286:1350-1352, 1972.Article
Better DS, Alroy GG, Chaimowitz C, et al:  Spontaneous remission of the defect in urinary acidification after cadaver kidney homotransplantation . Lancet 1:110-112, 1970.Article
Blaufox MD, Lewis EJ, Jagger P, et al:  Physiologic responses of the transplanted human kidney: Sodium regulation and renin secretion . N Engl J Med 280:62-66, 1969.Article
Greene JA Jr, Vander AJ, Kowalczyk RS:  Plasma renin activity and aldosterone excretion after renal homotransplantation . J Lab Clin Med 71:586-595, 1968.
Blaufox MD, Birbari AE, Hickler TB, et al:  Peripheral plasma renin activity in renal homotransplant recipients . N Engl J Med 275:1165-1168, 1966.Article
West TH, Turcotte JG, Vander AJ:  Plasma renin activity, sodium balance, and hypertension in a group of renal transplant recipients . J Lab Clin Med 73:564-573, 1969.
Margulis RM, Folkert OB, Kountz SL:  Surgical correction of renovascular hypertension following renal allotransplantation . Arch Surg 106:13-16, 1973.Article
Lee HM, Linehan D, Pierce JC, et al:  Renal artery stenosis and gastrointestinal hemorrhage in human renal transplantation . Transplant Proc 4:681-683, 1972.
Nagy EJ, Kolin A, Davidson JW, et al:  Tantalum angiography in experimental hyperacute renal xenograft rejection . Invest Radiol 9:356-373, 1974.Article
Pierce JC, Kay S, Lee HM:  Donor specific IgG antibody and the chronic rejection of human renal allografts . Surgery 78:14-21, 1975.
Alfidi RJ, Meaney TF, Buonocore E, et al:  Evaluation of renal homotransplantation by selective angiography . Radiology 87:1099-1104, 1966.Article
Smellie WAB, Vinik M, Hume DM:  Angiographic investigation of hypertension complicating human renal transplantation . Surg Gynecol Obstet 128:963-968, 1969.
Raphael MJ, Steiner RE, Shackman R, et al:  Post-operative angiography in renal homotransplantation . Br J Radiol 42:873-885, 1969.Article