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September 1977

Total Parenteral Nutrition Using Peripheral Veins in Surgical Neonates

Author Affiliations

From the Department of Pediatric Surgery, Kyushu University Hospital, Fukuoka, Japan.

Arch Surg. 1977;112(9):1045-1049. doi:10.1001/archsurg.1977.01370090027005

• A new program of total parenteral nutrition (TPN) for surgical neonates has been described and investigated. The program is based on the use of fat emulsion as the major source of calories and infusion of large volumes of the solution via peripheral veins. This program has three main advantages over conventional hyperalimentation using a central venous catheter: (1) it avoids complications such as septicemia, thrombosis of large vessels, and metabolic complications such as hyperglycemia or osmotic diuresis; (2) it provides physiological nutritive elements containing a normal composition of glucose, protein, and fat; and (3) it is easy to start and manage the TPN using a peripheral vein. Thirty-four neonatal surgical patients with life-threatening gastrointestinal anomalies have been placed on this TPN program. Infusion of fat emulsion and large volumes of fluid were well tolerated and all patients gained weight during the period of observation.

(Arch Surg 112:1045-1049, 1977)

Dudrick SJ, Wilmore DS, Vars HM, et al:  Long-term total parenteral nutrition with growth, development and positive nitrogen balance . Surgery 64:134, 1968.
Groff DB:  Complications of intravenous hyperalimentation in newborns and infants . J Pediatr Surg 4:460, 1969.Article
Heird WC, Driscoll JM, Schullinger JN, et al:  Intravenous alimentation in pediatric patients . J Pediatr 80:351, 1972.Article
Fletcher MJ:  A colorimetric method for estimating serum triglycerides . Clin Chim Acta 22:393, 1968.Article
Tashiro T, Ogata H, Yokoyama H:  The effect of fat emulsion on essential fatty acid deficiency during intravenous hyperalimentation in pediatric patients . J Pediatr Surg 10:203, 1975.Article
Borresen HC, Coran AG, Knutrud O:  Metabolic results of parenteral feeding in neonatal surgery: A balanced parenteral feeding program based on synthetic L-amino acid solution and commercial fat emulsion . Ann Surg 172:291, 1970.Article
Coran AG, Nesbakken R, Knutrud O:  The metabolism of intravenously administered fat in adult and newborn dogs . Surgery 66:922, 1969.
Reid DJ:  Intravenous fat therapy . Br J Surg 54:198, 1967.Article
Koga Y, Ikeda K, Inokuchi K:  Effect of complete parenteral nutrition including fat emulsion on plasma lipid . Surgery 76:278, 1974.
Rodgers BM:  Intrahepatic cholestasis with parenteral alimentation . Am J Surg 131:149, 1975.Article
Schuberth O:  Clinical experience with fat emulsion for intravenous use . Acta Chir Scand [ (Suppl) ] 325:43, 1964.
Jacobson S, Ericsson J, Obel A:  Histopathological and ultrastructural changes in human liver damage during complete intravenous nutrition for seven months . Acta Chir Scand 137:335, 1971.
Davidson M:  Formula feeding of normal term and low birth weight infants . Pediatr Clin North Am 17:913, 1970.
Fox HA, Krasna IH:  Total intravenous nutrition by peripheral vein in neonatal surgical patients . Pediatrics 52:14, 1973.
Kaplan MS, Mares A, Quintana P, et al:  High caloric glucose-nitrogen infusions: Postoperative management of neonatal infants . Arch Surg 99:567, 1969.Article